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Ion channel inhibition

Stronium is also believed to act as a pain relieving effect through its interaction with ion channel function. Neuronal discharge is regulated by the entry of calcium into cells via voltage dependant channels. Some divalent ions, such as strontium, mimic the ability of calcium to pass through the voltage dependant calcium channels. Strontium, located below calcium in the Periodic Table is a divalent cation that may compete with Ca++ for binding to some receptors. Calcium is thought to play a role in the pain process by regulating the release of chemicals that nerve cells use to communicate, and strontium would compete with calcium, potentially hindering entrance of calcium into the nerve cells.


Nerve cell

A nerve cell or neuron is an electrically excitable cell that processes and transmits information by electrochemical signalling. All neurons are electrically excitable, maintaining voltage gradients across their membranes by means of metabolically driven ion pumps, which combine with ion channels embedded in the membrane to generate intracellular-versus-extracellular concentration differences of ions such as sodium, potassium, chloride, and calcium.

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